• CytoCy5S™, a compound of many structures. in vitro and in vivo evaluation of four near-infrared fluorescent substrates of nitroreductase (NTR) 

      García de Jalón, Elvira; Ruiz de Garibay, Gorka; Haug, Bengt Erik; Mccormack, Emmet Matin (Journal article; Peer reviewed, 2021)
      CytoCy5S™, a quenched, red-shifted fluorescent probe, has been used to exploit the imaging potential of the nitroreductase (NTR) reporter gene platform. Its use has been reported in a number of publications, however there ...
    • Formulation and characterisation of drug-loaded antibubbles for image-guided and ultrasound-triggered drug delivery 

      Kotopoulis, Spiros; Lam, Christina; Haugse, Ragnhild; Snipstad, Sofie; Murvold, Elsa Thodesen; Jouleh, Tæraneh; Berg, Sigrid; Hansen, Rune; Popa, Mihaela-Lucia; Mccormack, Emmet Matin; Gilja, Odd Helge; Poortinga, Albert (Journal article; Peer reviewed, 2022)
      The aim of this study was to develop high load-capacity antibubbles that can be visualized using diagnostic ultrasound and the encapsulated drug can be released and delivered using clinically translatable ultrasound. The ...
    • Recommendations for robust and reproducible preclinical research in personalised medicine 

      Fosse, Vibeke Samuelsen; Oldoni, Emanuela; Bietrix, Florence; Budillon, Alfredo; Daskalopoulos, Evnagelos P.; Fratelli, Maddalena; Gerlach, Björn; Groenen, Peter M.A.; Hölter, Sabine M.; Menon, Julia M.L.; Mobasheri, Ali; Osborne, Nikki; Ritskes-Hoitinga, Merel; Ryll, Bettina; Schmitt, Elmar; Ussi, Anton; Andreu, Antonio L.; Mccormack, Emmet Matin (Journal article; Peer reviewed, 2023)
      Background Personalised medicine is a medical model that aims to provide tailor-made prevention and treatment strategies for defined groups of individuals. The concept brings new challenges to the translational step, both ...
    • SonoVue® vs. Sonazoid™ vs. Optison™: Which Bubble Is Best for Low-Intensity Sonoporation of Pancreatic Ductal Adenocarcinoma? 

      Kotopoulis, Spiros; Popa, Mihaela-Lucia; Mayoral Safont, Mireia; Murvold, Elsa Thodesen; Haugse, Ragnhild; Langer, Anika; Dimcevski, Georg Gjorgji; Lam, Christina; Bjånes, Tormod Karlsen; Gilja, Odd Helge; Mccormack, Emmet Matin (Journal article; Peer reviewed, 2022)
      The use of ultrasound and microbubbles to enhance therapeutic efficacy (sonoporation) has shown great promise in cancer therapy from in vitro to ongoing clinical studies. The fastest bench-to-bedside translation involves ...