Blar i Bergen Open Research Archive på forfatter "Mccormack, Emmet Matin"
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CytoCy5S™, a compound of many structures. in vitro and in vivo evaluation of four near-infrared fluorescent substrates of nitroreductase (NTR)
García de Jalón, Elvira; Ruiz de Garibay, Gorka; Haug, Bengt Erik; Mccormack, Emmet Matin (Journal article; Peer reviewed, 2021)CytoCy5S™, a quenched, red-shifted fluorescent probe, has been used to exploit the imaging potential of the nitroreductase (NTR) reporter gene platform. Its use has been reported in a number of publications, however there ... -
Formulation and characterisation of drug-loaded antibubbles for image-guided and ultrasound-triggered drug delivery
Kotopoulis, Spiros; Lam, Christina; Haugse, Ragnhild; Snipstad, Sofie; Murvold, Elsa Thodesen; Jouleh, Tæraneh; Berg, Sigrid; Hansen, Rune; Popa, Mihaela-Lucia; Mccormack, Emmet Matin; Gilja, Odd Helge; Poortinga, Albert (Journal article; Peer reviewed, 2022)The aim of this study was to develop high load-capacity antibubbles that can be visualized using diagnostic ultrasound and the encapsulated drug can be released and delivered using clinically translatable ultrasound. The ... -
Recommendations for robust and reproducible preclinical research in personalised medicine
Fosse, Vibeke Samuelsen; Oldoni, Emanuela; Bietrix, Florence; Budillon, Alfredo; Daskalopoulos, Evnagelos P.; Fratelli, Maddalena; Gerlach, Björn; Groenen, Peter M.A.; Hölter, Sabine M.; Menon, Julia M.L.; Mobasheri, Ali; Osborne, Nikki; Ritskes-Hoitinga, Merel; Ryll, Bettina; Schmitt, Elmar; Ussi, Anton; Andreu, Antonio L.; Mccormack, Emmet Matin (Journal article; Peer reviewed, 2023)Background Personalised medicine is a medical model that aims to provide tailor-made prevention and treatment strategies for defined groups of individuals. The concept brings new challenges to the translational step, both ... -
SonoVue® vs. Sonazoid™ vs. Optison™: Which Bubble Is Best for Low-Intensity Sonoporation of Pancreatic Ductal Adenocarcinoma?
Kotopoulis, Spiros; Popa, Mihaela-Lucia; Mayoral Safont, Mireia; Murvold, Elsa Thodesen; Haugse, Ragnhild; Langer, Anika; Dimcevski, Georg Gjorgji; Lam, Christina; Bjånes, Tormod Karlsen; Gilja, Odd Helge; Mccormack, Emmet Matin (Journal article; Peer reviewed, 2022)The use of ultrasound and microbubbles to enhance therapeutic efficacy (sonoporation) has shown great promise in cancer therapy from in vitro to ongoing clinical studies. The fastest bench-to-bedside translation involves ...